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| Michelle Nolden | Annette DeTamble | |
| Alex Ferris | Henry at Six | |
| Arliss Howard | Richard DeTamble | |
| Eric Bana | Henry DeTamble | |
| Katherine Trowell | Hospital Receptionist | |
| Bart Bedford | Library Researcher | |
| Esther Jun | Waitress | |
| Matt Birman | Chicago Police #1 | |
| Craig Snoyer | Chicago Police #2 | |
| Rachel McAdams | Clare Abshire | |
| Carly Street | Librarian | |
| Romyen Tangsubutra | Thai Waiter | |
| Brooklynn Proulx | Clare at Six and Eight | |
| Jane McLean | Charisse | |
| Ron Livingston | Gomez |
| Director |
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| Producer | Nick Wechsler
Richard Brener |
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| Writer | Bruce Joel Rubin
Audrey Niffenegger |
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| Cinematography | Florian Ballhaus
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| Musician | Mychael Danna
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Henry DeTamble (Eric Bana) is a Chicago librarian with an odd problem: he has a genetic disorder that sends him hurtling through time when he is under distress. In spite of this challenge, Henry tries to build a stable life with the woman he loves, Clare (Rachel McAdams). Though they are married, Henry disappears and reappears randomly throughout Clare's life. With the challenges of a regular relationship coupled on top of this difficult challenge, the two try to find a way to have a happy life together. |
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